Medically supervised ketamine infusion therapy has been found to reactivate existing connections and to grow new ones, helping the brain to “shake loose” negative thoughts and shift out of depression. Because the brain has actually been “reshaped,” it may explain why antidepressant medications that didn’t work in the past, may help after ketamine therapy.
Ketamine infusion therapy may be an option for patients with treatment-resistant depression that has not responded to traditional therapies, including medications and psychotherapy.
Although ketamine can be administered in many ways (oral, nasal spray and injection), intravenous (IV) infusion is the most extensively studied method to date. Ketamine treatment can be temporary or lifelong depending on a person’s treatment history and an evaluation of the risks and benefits.
Ketamine infusion therapy involves the administration of a single infusion or a series of infusions for the management of psychiatric disorders like major depressive disorder, post-traumatic stress disorder, acute suicidality. Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist.
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